Are there risks of excess supplementation/overdosing?
Ostelin® contains an approved daily dose of calcium and vitamin D that should be taken according to the dosing instructions.
Although the risk of overdosing on calcium is extremely low, excess levels of calcium should be avoided as this can lead to symptoms such as thirst, vomiting, nausea, constipation and fatigue.
The Geelong study showed that the average dietary calcium intake in women over 55 years of age is only 646mg. Considering that the recommended minimum daily intake is 1300mg in women over 50, there is large safety margin in the majority of patients. It is also worth pointing out that the Geelong study demonstrated that only 6.6% of Australian women took calcium supplements – at a time when Calcium was still PBS listed for Osteoporosis.
The majority of osteoporotic women you test for vitamin D insufficiency will require supplementation(LIPS ET AL). However, the risk of causing harm by supplementing a patient who is vitamin D replete is small. For example, rickets is often treated with 4,000 IU of oral vitamin D per day administered for approximately one month. Vitamin D toxicity does not usually occur until intakes of 50,000 IU or more per day are reached.